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Page 1
Bronchodilator efficacy of extrafine glycopyrronium bromide: the Glyco 2 study.
Singh D, Scuri M, Collarini S, Vezzoli S, Mariotti F, Muraro A, Acerbi D. Singh D, et al. Int J Chron Obstruct Pulmon Dis. 2017 Jul 7;12:2001-2014. doi: 10.2147/COPD.S137659. eCollection 2017. Int J Chron Obstruct Pulmon Dis. 2017. PMID: 28744115 Free PMC article. Clinical Trial.
For this endpoint, GB 25 and 50 mug BID were also superior to tiotropium. Compared with Day 7, addition of formoterol significantly increased Day 8 FEV(1) peak and AUC(0-12h) with all GB doses and placebo (all P<0.001). ...This study provides initial evidence on …
For this endpoint, GB 25 and 50 mug BID were also superior to tiotropium. Compared with Day 7, addition of formoterol signific …
Efficacy and Safety of Inhaled Glycopyrronium Bromide in COPD: A Randomized, Parallel Group, Dose-Ranging Study (GLIMMER).
Kerwin E, Feldman G, Pearle J, De La Cruz L, Edwards M, Beaudot C, Georges G. Kerwin E, et al. COPD. 2021 Apr;18(2):181-190. doi: 10.1080/15412555.2021.1894111. Epub 2021 Mar 12. COPD. 2021. PMID: 33709856 Clinical Trial.
Results for the secondary spirometry endpoints were consistent with the primary endpoint. Overall, the efficacy of GB 25 and 50 g BID was broadly consistent with that of tiotropium. ...
Results for the secondary spirometry endpoints were consistent with the primary endpoint. Overall, the efficacy of GB 25 and 5 …
Characterization of Poly(3-hydroxybutyrate) (P3HB) from Alternative, Scalable (Waste) Feedstocks.
de Sousa Junior RR, Cezario FEM, Antonino LD, Dos Santos DJ, Lackner M. de Sousa Junior RR, et al. Bioengineering (Basel). 2023 Nov 30;10(12):1382. doi: 10.3390/bioengineering10121382. Bioengineering (Basel). 2023. PMID: 38135973 Free PMC article.
PCC 6714) for photoautotrophic production and the other via methanotrophic bacteria (Methylocystis sp. GB 25) for chemoautotrophic growth. This research evaluates the thermal and mechanical properties, including the aging effect over 21 days, demonstrating that both …
PCC 6714) for photoautotrophic production and the other via methanotrophic bacteria (Methylocystis sp. GB 25) for chemoautotro …
Dose-response of an extrafine dry powder inhaler formulation of glycopyrronium bromide: randomized, double-blind, placebo-controlled, dose-ranging study (GlycoNEXT).
Beeh KM, Emirova A, Prunier H, Santoro D, Nandeuil MA. Beeh KM, et al. Int J Chron Obstruct Pulmon Dis. 2018 May 25;13:1701-1711. doi: 10.2147/COPD.S168493. eCollection 2018. Int J Chron Obstruct Pulmon Dis. 2018. PMID: 29872288 Free PMC article. Clinical Trial.
All four GB doses were also statistically superior to placebo for all secondary efficacy end points, showing clear dose-response relationships for most of the endpoints. Accordingly, GB 25 mug BID met the criteria for the minimally acceptable dose. Adverse events we …
All four GB doses were also statistically superior to placebo for all secondary efficacy end points, showing clear dose-response relationshi …
Effects of different carbohydrate sources on taurine status in healthy Beagle dogs.
Pezzali JG, Acuff HL, Henry W, Alexander C, Swanson KS, Aldrich CG. Pezzali JG, et al. J Anim Sci. 2020 Feb 1;98(2):skaa010. doi: 10.1093/jas/skaa010. J Anim Sci. 2020. PMID: 31943028 Free PMC article.
Total bile acid excretion was similar between GF and GB groups, but dogs fed GF excreted a higher proportion of primary bile acids compared with those fed GB (25.49% vs. 12.09% at day 28, respectively). In summary, overall taurine status was not affected by dietary …
Total bile acid excretion was similar between GF and GB groups, but dogs fed GF excreted a higher proportion of primary bile acids compared …
Acupuncture Improves Peri-menopausal Insomnia: A Randomized Controlled Trial.
Fu C, Zhao N, Liu Z, Yuan LH, Xie C, Yang WJ, Yu XT, Yu H, Chen YF. Fu C, et al. Sleep. 2017 Nov 1;40(11). doi: 10.1093/sleep/zsx153. Sleep. 2017. PMID: 29029258 Clinical Trial.
Interventions: A 10-session of acupuncture at bilateral Shenshu (BL 23) and Ganshu (BL 18) with unilateral Qimen (LR 14) and Jingmen (GB 25) or Streitberger needles at the same acupoints was performed for over 3 weeks. ...
Interventions: A 10-session of acupuncture at bilateral Shenshu (BL 23) and Ganshu (BL 18) with unilateral Qimen (LR 14) and Jingmen (GB …
The Effect of Glycine Betaine on Nitrogen and Polyamine Metabolisms, Expression of Glycoside-Related Biosynthetic Enzymes, and K/Na Balance of Stevia under Salt Stress.
Ghorbani A, Ghasemi-Omran VO, Chen M. Ghorbani A, et al. Plants (Basel). 2023 Apr 12;12(8):1628. doi: 10.3390/plants12081628. Plants (Basel). 2023. PMID: 37111852 Free PMC article.
The present study was conducted under in vitro conditions to evaluate the effect of GB (25 and 50 mM) on the growth, physiological, and molecular traits of Stevia rebaudiana during NaCl toxicity (50 mM). ...
The present study was conducted under in vitro conditions to evaluate the effect of GB (25 and 50 mM) on the growth, physiolog …
Purification and properties of methanol dehydrogenase from Methylocystis sp. GB 25.
Grosse S, Wendlandt KD, Kleber HP. Grosse S, et al. J Basic Microbiol. 1997;37(4):269-79. doi: 10.1002/jobm.3620370406. J Basic Microbiol. 1997. PMID: 9323867
Methanol dehydrogenase (MDH) from Methylocystis sp. GB 25, which belongs to the group II of methanotrophic bacteria, is able to catalyse the oxidation of methanol to formate directly. ...The purified MDH has an optimum activity at pH 9.0 and at 45 degrees C. MDH of …
Methanol dehydrogenase (MDH) from Methylocystis sp. GB 25, which belongs to the group II of methanotrophic bacteria, is able t …
Exogenous glycine betaine alleviates water-deficit stress in Indian pennywort (Centella asiatica) under greenhouse conditions.
Chungloo D, Tisarum R, Samphumphuang T, Pipatsitee P, Sotesaritkul T, Cha-Um S. Chungloo D, et al. Protoplasma. 2024 Jan 11. doi: 10.1007/s00709-023-01919-6. Online ahead of print. Protoplasma. 2024. PMID: 38206421
At the flower-initiation stage (30 days after transplantation), uniform plant material was treated exogenously with 0 (control), 25, and 50 mM GB at 100 mL per plant (one-time foliar spray) and then divided into two groups, 1) well watered (WW; irrigated daily with 400 mL fresh w …
At the flower-initiation stage (30 days after transplantation), uniform plant material was treated exogenously with 0 (control), 25, and 50 …
Simultaneous determination of eight bioactive compounds by LC-MS/MS and its application to the pharmacokinetics, liver first-pass effect, liver and brain distribution of orally administrated Gouteng-Baitouweng (GB) in rats.
Tian X, Xu Z, Chen M, Hu P, Liu F, Sun Z, Liu H, Guo X, Li Z, Huang C. Tian X, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2018 May 1;1084:122-131. doi: 10.1016/j.jchromb.2018.03.013. Epub 2018 Mar 9. J Chromatogr B Analyt Technol Biomed Life Sci. 2018. PMID: 29597038
This method elicited good linearity for the analytes at the concentration range of 0.3-1000 or 1.8-6000 ng/mL with favorable precision, accuracy and stability. Following oral administration of GB (25 g/kg) in rats, this method was applied to the quantitative analysi …
This method elicited good linearity for the analytes at the concentration range of 0.3-1000 or 1.8-6000 ng/mL with favorable precision, accu …
26 results